German trying to use PT to lower Lp(a) without success

The discussion of the Linus Pauling vitamin C/lysine invention for chronic scurvy

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pamojja
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Re: German trying to use PT to lower Lp(a) without success

Post Number:#211  Post by pamojja » Sun Dec 23, 2018 9:34 am

The challenge is she doesn't want. I knew a hundred ways how to counter pancreatic cancer. Though I can understand that she doesn't want to undertake such drastic measures, like an immediate fast, ketogenic diet, IVs, pancreatic enzymes, turkey tail or other supplements by the hand-full. But she even refuses an easy to take (because it only needs a speck of a tablet) immune booster like LDN. She is just happy to finally being able die for the reasons already mentioned above.

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#212  Post by Frodo » Tue Jan 08, 2019 10:02 am

Owen, Johnwen

At post 206 I wrote:

„I see it‘s working (with actually about 30 grams VC, 7 grams lysine and 2 grams proline, additional about 1,5 grams niacin).“

Once again my question: What do you think, should I try to increase niacin?

Thanks for your answer. I hope it could be helpful.

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#213  Post by ofonorow » Wed Jan 09, 2019 5:42 am

Thanks to the book NIACIN: THE REAL STORY, by Hoffer, Saul, et. al., taking the right amount of Niacin is important, whether or not it provides any other added benefits visa via Lp(a) and heart disease.

Hoffer used to match his vitamin C and Niacin dosage recommendations (from his other books.) In his book about Cancer and Vitamin C, which is a collection of case reports, I believe his general recommendations were 6 g ascorbate and 6 g niacin.

For those readers who don't know, it was Hoffer's book on using high doses of Niacin to treat schizophrenia that opened the eyes of Linus Pauling, creating his interest that led to orthomolecular medicine. How, Pauling wondered, could a substance that was so physiologically powerful that a spec could cure a deficiency disease, e.g. pellegra, be taken at doses several orders of magnitude larger (e.g. 18 grams) and not have any toxic effects?

Hoffer explains his theory in NIACIN: THE REAL STORY, i.e., that perhaps 1/3 of the population has a genetic defect that causes mental problems, and that some dosage of Niacin corrects.
Owen R. Fonorow, Follow #OWENRFONOROW at twitter

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#214  Post by Frodo » Tue Feb 05, 2019 4:33 am

Owen

A stupid question. But at least a chief physician of cardiology asked this question. After my heart attack two years ago. He wanted to have my VC status determind. Because I had told him that I was taking 30 grams of VC. And he didn‘t understand that, of course.
According to everything I know, this is nonsense.
Or is there a way to measure VC in the body (except the method of Cathcart or Jaffe)?

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#215  Post by ofonorow » Wed Feb 06, 2019 7:20 am

Not a stupid question, or at least it is a question I personally have trouble answering :?

There are tests for vitamin C blood levels.. If we think of kidneys as a bucket with a hole near the top (thank you Drs. Hickey and Saul) then when vitamin C levels are below the level of the hole (e.g. between 0 and 1.5 mg/dl) we have some idea of vitamin C "status." (When we take more and fill the "bucket" up more than the hole, the extra is quickly eliminated via the kidneys/urine.)

If cells require vitamin C they will extract it from the blood. If it is not resupplied, the blood level declines. We know from Cathcart that when ill or under stress, our tissues can extract massive amounts of the vitamin from the blood.

So the closer blood levels are to 1.5 mg/dl - the more saturated are our tissues and the better our vitamin C status is.

The Dynamic Flow theory (e.g. 30 minute half-life) indicates that at some level of consistent intake, the blood level can be kept at or near the hole (1.5 mg/dl), perhaps 500 mg every 4 hours.
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Re: German trying to use PT to lower Lp(a) without success

Post Number:#216  Post by pamojja » Wed Feb 06, 2019 10:29 am

http://www.longecity.org/forum/topic/91 ... ntry797721

The patients had been encouraged as part of their treatment to supplement AA. Self-reported daily intake varied from 0 to 20 g/day. The plasma AA levels ranged from 11.4 to 517 µmol/L and correlated well with the reported intake. Regression analysis of their GHb and plasma AA values showed a statistically significant inverse association (eg, each 30 µmol/L increase in plasma AA concentration resulted in a decrease of 0.1 in GHb).


According to http://www.endmemo.com/medical/unitconv ... amin_C.php 517 micromol/L are 9.1 mg/dl of Vitamin C consistently tested in Plasma of patient who have taken 20 g of Vitamin C throughout the day.

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#217  Post by Frodo » Wed Feb 06, 2019 4:48 pm

OK and thank you Owen.

But that only makes sense if I take VC and want to check how it works out. And I should have done it just in time. But during my stay at the clinic there was no VC. Only bad clinic nutrition. Therefore I think that it makes no sense to measure it.

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Re: German trying to use PT to lower Lp(a) without success

Post Number:#218  Post by ofonorow » Sat Feb 09, 2019 12:41 pm

Well, your doctor might learn something if you -- who takes such a large amount-- shows low on a blood test :-)

There is an oxidative stress test (that measure GSH I believe) that may be an indicator. Boyd Haley told us that only vitamin C can regenerate or increase GSH levels in cells. So if your oxidative stress is low, you could infer your vitamin C status within cells is good.

We might be able to invent some kind of loading test, along the lines of the Jaffe Cleanse, to evaluate how much (and fast) vitamin C is entering tissues, as a measure of current status.

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