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More Glucose/No Vitamin C: Split from On Pauling Therapy but my Cholesterol is too high for my Cardiologist

Posted: Tue Dec 25, 2018 2:12 pm
by confused1
Sorry, totally off topic, but thinking of diabetes has me wondering if anyone knows the percentage of glucose in animals that is converted to vitamin c? Since we are missing the GULO gene, not only are we not making vitamin c but it would seem we are getting bombarded with glucose in our bloodstream that would have been converted to c.

Re: More Glucose/No Vitamin C: Split from On Pauling Therapy but my Cholesterol is too high for my Cardiologist

Posted: Thu Jan 03, 2019 6:28 am
by ofonorow
Separated this question into its own topic because I know this observation is a favorite for our member RalphDMan :D . It is relevant to the new product, name escapes me, whose makers believe can stimulate the production of ascorbate from glucose, either by reactivating GULO or other means.

One thing I note is that in humans, the ideal blood glucose is regulated to 90 mg/dl, while the highest vitamin C level is 1.5 mg/dl. So optimal ascorbate is roughly 1 to 2 percent of the glucose in the blood. Even if our livers made more ascorbate (from our now very high sugar intakes) the kidneys would regulate it to no more than 1.5 mg/dl over a short time (30 minute half life).

Re: More Glucose/No Vitamin C: Split from On Pauling Therapy but my Cholesterol is too high for my Cardiologist

Posted: Thu Jan 10, 2019 7:54 am
by confused1
I can't find it again now, but I found a study that showed slightly over 90% of glucose was converted to vitamin c during extreme stress in animals.