What does 10,000mg AA do to body pH?

Any adverse effects of replacement vitamin C will be discuseed here. Topics include kidney stones, gall stones, oxidation, etc.
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Ascorbate Wizard
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What does 10,000mg AA do to body pH?

Post Number:#1  Post by ofonorow » Wed Nov 29, 2006 10:37 am

Especially interesting email question from an MD in Germany..

Dear Sirs,
What happens to the pH of the blood when people take 10 grams or more of Vitamin C ?
S. B., MD

Dear Dr. B.,

Good question, and hopefully members of this forum will be able to improve on the following response. My understanding is as follows:

1) keep in mind that virtually all animal livers (or some kidneys in lower forms) produce ascorbic acid 24/7. I once estimated the average amount produced to be equivalent to 250 mg/hr (We humans would have to take 500 mg/hr by mouth to achieve roughly equivalent blood levels).

2), the greatest chemist of our time ingested 9,000 (almost 10,000 mg) at one time, and did this twice per day for a total of 18,000 mg daily (Source: HOW TO LIVE LONGER AND FEEL BETTER, 1986) It is true that Pauling buffered this amount with an unspecified amount of sodium bicarbonate.

3), ascorbic acid is a weak acid, and the kidneys regulate the maximum blood level of AA to around 15 mg/dl, where it begins to spill into the urine in most people. This is still about 1/10 the amount of glucose in the blood.

4) , ascorbate travels in both acid and alkaline form, e.g. it is combined with sodium in the liver and at least part of the vitamin C in the body travles through the blood as sodium ascorbate - an alkaline substance.

5), Pauling estimated (and Sherry Lewin concurs) that approximately one half of the vitamin taken by mouth is "lost" (reacts with something) before entering the blood stream.

We believe, based on Dr. Cathcart's writings, and his video lecture
http://www.vitamincfoundation.org/videos , that ascorbic acid is the most potent form of vitamin C for putting out free radical fires. In other words, AA is best for achieving maximum therapeutic effects. However, sodium ascorbate
is also vitamin C (though only about half as effective). Sodium ascorbate can be taken orally, and it is alkaline - not acidic at all.

Pauling's advice, in a discussion of kidney stones, seemed to be to monitor the pH of the urine. If the urine is too alkaline - then ascorbic acid can help PREVENT kidney stones. If the urine is too acidic, then he recommended the sodium ascorbate form of vitamin C.
Owen R. Fonorow, Orthomolecular Naturopath

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Joined: Fri Nov 25, 2005 3:01 am

Post Number:#2  Post by Dolev » Fri Dec 01, 2006 12:44 am

The acidity of the blood is one of the most highly regulated balances in the body. Besides the kidney's role, acid-base balance is regulated by the respiratory system (exhalation of CO), and by various buffers. A buffer is a pair of substances which resist change in acidity by either releasing or accepting H+ ions. One of many buffers is the bicarbonate (HCO3- and carbonic acid H2CO3) pair. Amino acids also buffer. The amount of acid needed to raise the pH of the blood to a state of acidosis would be huge. Don't worry about vitamin C doing this. A great source to learn about this and physiology in general is "The Physiology Coloring Book".

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