I wish Dr. Ames would write a book (and if he already has, please let me know).
Dr. Bruce Ames made headlines years ago after announcing (in jest) that his group had made old rats start "dancing the macarena". They demonstrated the acectyl-l-carnitine (at high dosage) and lipoic acid (at high dosage) together seemed to reverse the aging process in laboratory animal experiments. (I have been looking for those photographs - before (old looking) and after (younger looking) and if anyone can find them, please post the link (as pictures really are worth a thousand words.)
While looking for these photos, I found this wonderful youtube lecture given by Dr. Bruce Ames. This lecture describes his group's work, how they measure, and what they found regarding age Reversal. Dr. Ames calls his theory of mitochondrial aging the "Triage Theory."
Ames group was focused on mitrochondrial aging, so it is natural for them to assume that improving the function of the 500 or so mitochonria in every cell was the reason for their spectacular anti-aging and age-reversal results. After I read Ed Parks and Bill Andrews book, I wondered ... perhaps these nutrients (ALC/ALA) worked by increasing the length of telomeres?
We may be in a position to soon find out.