The TrifecTA Study Begins

[ofonorow]

[ofonorow]

These are pointers to two important new topics in our new life extension forum:

TrifecTA Liposomal Activator Study Begins
http://www.vitamincfoundation.org/forum/viewtopic.php?f=24&t=11815&p=39189#p39189

Error in Telomere Measurement (email from Bill Andrews)
http://www.vitamincfoundation.org/forum/viewtopic.php?f=24&t=11818


The first link to the study includes my wife and my first (baseline) Life Length telomere test results and a discussion.

The second link by Bill Andrews is a must read about Telomere Length measurements.

We are not making a product announcement about our new liposomal TrifecTA product, at least until after preliminary follow-on testing confirms what we believe - that our product contains the same molecule as TA-65. However, it was expensive to develop and we are making it available to brave souls early who are willing to take the chance that we are betting on: https://inteligentvitaminc.com//cart/index.php?main_page=index&cPath=21

[gofanu]

Owen-
Things to consider, ref post 2
Maybe a few monkey wrenches here, sorry.

"Here are some things I have noticed since I got my nutrition near current 2007, plus glitches 2009 when I put the I/Se way up.

1. I require less sleep. Always a night person. midnight to 4am best. Now, I seem to never get to sleep until 6am or later. It was and is hard to interact with the normal world! I slept 16+hr/d and could not stay awake two hr straight, after I stopped my life threatening trucking career, 1990. After a year I got to around ten hr as normal. That stayed the need, though all too often not the achievement. When I raised Mg from 250 to 750mg/d in 2007, sleep dropped to 8hr. Adding iodine 25mg/d dropped it to 5hr 15min, exactly, self wakening. I can go back to sleep for another 1 1/2 hr, but do so only if it is really cold or pouring rain, etc.
Mind? Well, all the stuff I write here is straight out of my head, and I do the same in another completely unrelated realm, or two, maybe three.

2. Vivid dreaming - I have rarely had remembered dreams, and that has not changed through all of this. The few I do have are very vivid though.

"Some things I am hoping the liposomal TA activator will help with, in addition to all the existing benefits I enjoy from my high vitamin C intake."

"1. My hair is all grey." My hair/beard was dead white from 1995, I was in another very high stress situation. Stayed that way until the 2009 iodine/Se jump, when colour returned. Dark in beard, the blond of my childhood on head, grey throughout.


"2. Gland rejuvenation." Skin/hair is properly oiled, not too much, not too little. Hair loss dropped from lifetime normal by 90% when I added iodine at around 25mg/d. Same for dog, cats, people. This was noticeable-obvious in two days from start. Salivary glands work as never in my life.
Lacrimal glands too. Mucosa are all notably wetter, have to blow nose a little bit often, but it never gets clogged up. Sort of like a healthy dog!

"On the same order, my adrenal output of cortisol is "insufficient" and must be supplemented. If my adrenal glands are rejuventated, I would potentially be able to tell by slowly reducing my hydrocortisone and feeling whether that triggers inflammation, particularly in my fingers and joints."
I have no pain, inflammation, or other sign of low adrenal/cortisone/cortisol since 2001, when I figured out the AA/Magnesium/calcium/panto pain treatment. Any change to this with iodine/selenium was slight but for the better. I can now go 48hr without sleep, working hard, and a 5:15 sleep leaves me feeling normal. I used to do that and it took several lazy days to recover.

"3. Sex Drive/Libido." Lets just say that I have more than I have anything to do with it - as high or higher than anytime in my life.

"If others have any ideas for items (questions) we should include on our study questionnaire, we would appreciate it."
I think you need to include these nutritional items in any such investigations.
Good luck with this interesting experiment, though I see it as possibly repairing that which need not be broken.
One thing I have learned in my other life - Maintenance is cheaper and better than repair.

FRM

[gofanu]

Double post - computer f-up, sorry!

[ofonorow]

[ofonorow]

[ofonorow]

[ofonorow]

[ofonorow]

[ofonorow]

One of our early drop-outs had his second Life Length test, and the results are encouraging. 3rd follow-up (Me, my wife and this male drop out)

The interesting thing is that his median telomere length went from "very short" to normal for his age, from 7.5Kb to 8.8Kb !!!

[ofonorow]

[ofonorow]

The second round of blood testing begins, and unfortunately, for legal reasons, we may not be able to share the results (which will require at least one month to process.) It is a little earlier than we planned, but it should provide us with a go/no go.

Here is pictorial proof of (most) of the bottles my wife and I consumed until yesterday. We did throw some away before I got the idea to preserve them for this picture. (And after the last blood draw, my wife reduced her consumption.) I have remained on more than 10 servings daily without any problems that I am aware of.

[ofonorow]

We have the first report (of the second round of tests) for a 48+ year old woman whose telomeres were very short for her age. This woman was key.

She saw her shortest telomeres increase by 400 base pairs in only six months. (Her median length also increased.)

Keep in mind that telomeres are only supposed to shorten, with various life style changes known that may delay the shortening.

While this woman was key, we are very anxious for the rest of the results to come in. Almost all should be available in the next day or two,


For the record, this woman was on a high dosage (10 servings) for a couple of months, to give us every chance of seeing a positive result in such a short time. Note if this rate holds among others in the study group, then we would anticipate it possible to increase by 1,000 base per year, and if you know your current telomere lengths, you can calculate how long it would take to reach the 10,000 (teenage) bench mark.

[ofonorow]

Another report to me is staggering, so I am violating legal advice to keep this quiet.

Code: Select all

IL  1002 Female Age 65  Median  Telomere Length 11.0  Criti. Short Telomeres (20%) 5.9

This woman is a medical doctor, was compliant, and told me she was taking most of what was in TrifecTA before entering the study.

Code: Select all

Summary

First Test:     Median Length 11.0          (May 2015)
Second test:   Median Lenth 12.5   !!!  (Sept 2015)

First Test:      Short Telomeres 5.9        (May 2015)
Second Test:  Short Telomeres  6.6  !!!  (Sept 2015)

?First Test:  Estimated Age: ?  64.8         (May 2015)
Secont Test: Estimated Age:   60.8 !!!  (Sept 2015)

This result was in roughly 4 months. .7 KB increase in short telomeres
1.5 KB increase in median telemore length.

So my curiosity is what else this alternative medical doctor does that may have amplified the effect? (If I learn, I will report)

[ofonorow]

Thinking about our results so far.

All women who have remained in our study have extended/grown their telomeres (in a very short time as far as these studies go.)

All the men have remained constant, but we have not demonstrated any lengthening in our telomeres (yet) even with high compliance and large dosages.

Re: male vs females, other than body weight, the other difference is hormonal.

In my case, with no lengthening of telomeres, other than a small darkening of my beard near the mustache, requirement for less sleep and the coincidental weight loss, there have been no noticeable anti-aging effects. (Ed Park reported that it took five years for his telomeres to grow, and they declined during the first year.) This makes it a very tough sell. The only way I can see for a man to determine this expensive product is working is by monitoring with very expensive telomere length testing, and we still don't have a positive result in a man after about 9 months.

As far as the Bruce Ames "ALC and ALA" components, the results are as mentioned, thus dissappointing.