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Re: German trying to use PT to lower Lp(a) without success
Posted: Wed Sep 27, 2017 12:46 pm
by Frodo
Yes, I also think it isn't possible to separate. But I've asked Roche (Prof. von Eckardstein) - they measure nmol - and Ganzimmun - they measure g/l with nelometer - what they think about it. I'd like to see their answer
and I'll report.
Re: German trying to use PT to lower Lp(a) without success
Posted: Thu Sep 28, 2017 8:42 am
by Frodo
I got an answer from Prof. Eckardstein. He says, that nephelometry isn't per se problematic. The basic problem is the difficult standardization of lp(a) measurement. According to Prof. Eckardstein a good summary of this problem can be found at
https://www.ncbi.nim.nih.gov/pubmed/26637278.
It appears to me, that I took up a very interesting (and important) question.
Re: German trying to use PT to lower Lp(a) without success
Posted: Thu Sep 28, 2017 8:40 pm
by skwoodwiva
Link seems to be broken.
Re: German trying to use PT to lower Lp(a) without success
Posted: Fri Sep 29, 2017 5:58 am
by Frodo
Re: German trying to use PT to lower Lp(a) without success
Posted: Fri Sep 29, 2017 6:39 am
by Frodo
Today I had a telephone call with Prof. Scharnagl, Medical University Graz. He also said that the basic problem is the difficult standardization of lp(a) measurement. According to Prof. Scharnagl, it does not have to do with the separation of LDL. Lp(a) can be distinguished from this. The reason for the problem is the repetitive kringle structure of apo(a) protein.
OK. But now I don't know furthermore which of my lab values are correct.
Re: German trying to use PT to lower Lp(a) without success
Posted: Sat Sep 30, 2017 5:58 am
by ofonorow
Although from what you sent me - the nmol/l is probably accurate and thus elevated. And no matter, taking Lp(a) binding inhibitors is warranted, and over time, I suspect the Lp(a) will decline.
Re: German trying to use PT to lower Lp(a) without success
Posted: Sat Sep 30, 2017 7:40 am
by Frodo
Thank you, Owen. I see that too. And I'll continue to report at the forum.
To provide complete information, the article from Prof. von Eckardstein:
https://academic.oup.com/eurheartj/arti ... oprotein-a (I hope it's correct)
But take into consideration, it's school medicine.
Re: German trying to use PT to lower Lp(a) without success
Posted: Sat Sep 30, 2017 10:31 am
by Johnwen
Re: German trying to use PT to lower Lp(a) without success
Posted: Sat Sep 30, 2017 1:22 pm
by Frodo
Good advice! Thank you. I'll make sure when I check my value next time. I hope, I'll find a suitable lab in Germany.
Re: German trying to use PT to lower Lp(a) without success
Posted: Fri Oct 06, 2017 2:58 pm
by Frodo
It seems to me, that my post is of great interest. More than 6.000 klicks within 9 months. I hope, that it is helpful for you. Furthermore I'm sure, my lp(a) will decline with PT. And I'll report. But much more important, after my heart attack one year ago the damaged part of my heart muscle has begun to work again. No angina. No problems. And I'm fit. Every day 1 to 2 hours nordic walking, muscle training and riding a bike, although I'm 70 years old - sorry, young. And I learned, I can all if I believe it.
Re: German trying to use PT to lower Lp(a) without success
Posted: Wed Oct 11, 2017 9:12 am
by Frodo
Re: German trying to use PT to lower Lp(a) without success
Posted: Sun Oct 22, 2017 8:50 am
by Frodo
From the meeting with Dr. Rath in Sept. 2017 in Leimen/Germany I have taken with me the german version of the article about lp(a) and arteriosclerosis in transgenic mice. And I have read it again. It is very interesting. And it shows and proves, cholesterol isn't the culprit. With PT we are on the right way. I think, that you know the study from Dr. Rath. If not, here is the link to the orginal english version: ajcd.us/files/ajcd0007056.pdf
Otherwise, it is worth to read the study again.
Re: German trying to use PT to lower Lp(a) without success
Posted: Sun Oct 22, 2017 8:52 am
by Frodo
Re: German trying to use PT to lower Lp(a) without success
Posted: Mon Oct 23, 2017 5:45 am
by ofonorow
Frodo wrote:It seems to me, that my post is of great interest. More than 6.000 klicks within 9 months. I hope, that it is helpful for you. Furthermore I'm sure, my lp(a) will decline with PT. And I'll report. But much more important, after my heart attack one year ago the damaged part of my heart muscle has begun to work again. No angina. No problems. And I'm fit. Every day 1 to 2 hours nordic walking, muscle training and riding a bike, although I'm 70 years old - sorry, young. And I learned, I can all if I believe it.
Thank you. Another anecdote for our "collection" 
As far as the connection between thyroid, LDL and Lp(a). It is my understanding that Lp(a) *IS* LDL cholesterol, but that a new surface has been attached to the lipoprotein, made up of apo(a) - thus Lp(a). The University of Chicago found, after Pauling died, that the apo(a) binds to LDL via proline binding sites. I am not chemist and do not pretend to be one on the Internet, but it seems the same logic Pauling used to increase lysine in the blood (knowing Lp(a) bindings sites are what sticks to collagen residues on the arteries) applies, and that increasing proline might interfere with the production of Lp(a) in the liver.
Re: German trying to use PT to lower Lp(a) without success
Posted: Sun Oct 29, 2017 7:42 am
by Frodo
Another question: In addition to PT I take a number of nutrient capsules. Most of them contain magnesium stearate.
Does anyone know if magnesium stearate is harmful?