Telomere Homeostasis: Interplay with Magnesium

Discussion of the 2009 Noble Prize in Medicine, focusing on substances that reduce telomere shortening by activating the human telomerase enzyme

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Telomere Homeostasis: Interplay with Magnesium

Post Number:#1  Post by ofonorow » Sat Jan 06, 2018 6:39 am

Owen R. Fonorow, Orthomolecular Naturopath

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Re: Telomere Homeostasis: Interplay with Magnesium

Post Number:#2  Post by pamojja » Sun Jan 07, 2018 6:40 am

zarfas wrote:can somesome tell a laymen what this means?

take more Magnesium?
how much?


Don't know what this implies, but it general some Mg supplemented is needed. The correct amount can be most accurately measured with red blood cell (RBC) Mg. Where the normal lab range is 4.2 - 6.8 mg/dl, optimal for health would be >6. Serum Mg allegedly isn't very accurate for measuring it, since it is tightly regulated in serum. Normal for serum would be something like 0.66 - 1.07 mmol/mol. However, also here there are studies which show that all-cause mortality greatly decreases with serum levels >0.86. Finally, RBC Mg tests are not everywhere available, in which case a whole blood Mg test, which is just the combination of RBC and serum, could substitute.

How much would be needed to get at optimal values is highly individual. For example in my case with a severe deficiency in Mg supplementing above 2 g/d of elemental Mg just prevented most pain-full muscle-cramps, but didn't budge levels in blood even a bid. I'm getting Mg-sulfate IVs for correcting that now.


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