Humans producing vitamin c

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johnyascorbate
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Humans producing vitamin c

Post Number:#1  Post by johnyascorbate » Wed May 30, 2018 7:11 am

Will we again one day have the ability to produce vitamin c? If so, how do you think that will happen?

ofonorow
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Re: Humans producing vitamin c

Post Number:#2  Post by ofonorow » Wed May 30, 2018 2:27 pm

johnyascorbate wrote:Will we again one day have the ability to produce vitamin c? If so, how do you think that will happen?


Van Carmen (who we haven't heard from in a while) was convinced that cinnamon could imitate the missing enzyme that our liver is unable to make, or actually contained the enzyme.

Be nice to know if Van was correct.

The problem with simply activating the gene by correcting the base pair through genetic engineering is that the GULO gene is old, and so doesn't have the benefit of recent evolution. But if available - for offspring I suppose - I would opt for it.

And yes, Levy reports that there may be certain small societies that can make their own vitamin C.
Owen R. Fonorow, Orthomolecular Naturopath

johnyascorbate
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Re: Humans producing vitamin c

Post Number:#3  Post by johnyascorbate » Thu May 31, 2018 7:22 am

ofonorow wrote:
johnyascorbate wrote:Will we again one day have the ability to produce vitamin c? If so, how do you think that will happen?


Van Carmen (who we haven't heard from in a while) was convinced that cinnamon could imitate the missing enzyme that our liver is unable to make, or actually contained the enzyme.

Be nice to know if Van was correct.

The problem with simply activating the gene by correcting the base pair through genetic engineering is that the GULO gene is old, and so doesn't have the benefit of recent evolution. But if available - for offspring I suppose - I would opt for it.

And yes, Levy reports that there may be certain small societies that can make their own vitamin C.


I fell out of my chair reading cinnamon could be the missing link. Did Van have anything to back that up? Would be nice if he was correct. I believe Dr. Levy is right, that some people walking among us make their own C. I'm hopeful one day through science we can make this a reality.

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Re: Humans producing vitamin c

Post Number:#4  Post by pamojja » Thu May 31, 2018 7:47 am

ofonorow wrote:Van Carmen (who we haven't heard from in a while) was convinced that cinnamon could imitate the missing enzyme that our liver is unable to make, or actually contained the enzyme.


I remember him - Van Carman - talking about olive leaf extract instead of cinnamon. However, most of his posts are gone and couldn't find even one mention anymore.

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Re: Humans producing vitamin c

Post Number:#5  Post by ofonorow » Thu May 31, 2018 2:00 pm

This from the top ten https://vitaminc.foundation/topten.php
#2
When blood levels are measured, the study results are consistent:

Older Brits with Highest Blood Levels of Vitamins C have Lowest Mortality Rates
A 2003 study from the UK measured Vitamin C blood levels:

RESULTS: Strong inverse relationship for blood ascorbate (vitamin C) concentrations with all-cause and cardiovascular disease mortality, Those in the lowest fifth (< 17 micromol/L) had the highest mortality, whereas those in the highest fifth (> 66 micromol/L) had a mortality risk nearly half that (hazard ratio = 0.54; 95% CI: 0.34, 0.84). In fully adjusted models, there was no evidence for an influence of alpha-tocopherol (vitamin-E), beta-carotene, or retinol (vitamin-A) on total mortality.

Antioxidant Vitamins and Mortality in Older Persons
https://www.ncbi.nlm.nih.gov/pubmed/14594788?dopt=Abstract


Americans with Highest Blood Levels of Vitamins C and E have Lowest Mortality Rates

Another recent study at Columbia University measured vitamin C blood levels and was reported by Bill Sardi: The group with the highest blood concentration of vitamin C were 45% less likely to die of any cause ; vitamin E 29% lower death risk compared to adults with the lowest blood concentration. The highest blood concentration of vitamin C also resulted in a relative 60% reduced risk for cancer-related deaths. http://knowledgeofhealth.com/americans-highest-blood-levels-vitamins-c-and-e-have-lowest-mortality-rate/


These blood measurement studies (as opposed to food questionnaire-based studies) would have made Linus Pauling happy. Pauling wrote that even though he couldn't prove it, he had become convinced that supplementing high doses of vitamin C, along with other antioxidants, might extend the healthy life span 20 to 30 years." (ref: How To Live Longer and Feel Better, 1986)

Plasma vitamin C concentrations predict 42% lower risk of incident stroke over 10 y in 20,649 participants
http://www.ncbi.nlm.nih.gov/pubmed/18175738

Then there is the Enstrom review of public health data that Pauling discusses on the Heart Video, showing a significant reduction in mortality when people take vitamin C supplements.

Vitamin supplement use and mortality. 1. Study that found no relationship is challenged.
https://www.ncbi.nlm.nih.gov/pmc/articl ... 46/?page=2

High levels in the blood of one other vitamin has been shown to reduce mortality: Vitamin K

High Vitamin K Blood Levels Reduce All Cause Mortality.
http://www.lef.org/magazine/2014/9/The-Surprising-Longevity-Benefits-of-Vitamin-K/Page-01
Owen R. Fonorow, Orthomolecular Naturopath

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Re: Humans producing vitamin c

Post Number:#6  Post by confused1 » Sun Jun 03, 2018 5:46 am

ofonorow wrote:
johnyascorbate wrote:Will we again one day have the ability to produce vitamin c? If so, how do you think that will happen?


Van Carmen (who we haven't heard from in a while) was convinced that cinnamon could imitate the missing enzyme that our liver is unable to make, or actually contained the enzyme.

Be nice to know if Van was correct.

I looked up Van in the members section and it shows he made 600 posts but only 35 are available. Any way to access the others, Owen?

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Re: Humans producing vitamin c

Post Number:#7  Post by confused1 » Sun Jun 03, 2018 6:18 am

Just thinking out loud, but could this be one of the mechanisms by which cinnamon lowers blood sugar, i.e., converting some fraction of glucose to AA?


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