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Do statin drugs mimic a vitamin?
Posted: Mon Jan 21, 2008 7:21 am
by Ralph Lotz
Re: Do statin drugs mimic a vitamin?
Posted: Wed Jan 23, 2008 10:35 am
by ofonorow
Does Bill include the molecular diagrams?
I thought that the drug companies patterned statins after vitamin C after reading the 1986 Harwood study, which showed that vitamin C is an HMG CoA Reductaste inhibitor (statin)
Also, I think vitamin D (and vitamin C) work much better than statins, that is, when you take statins your atherosclerotic plaques invariably become "more complex".
Something tells me that vitamins C/D don't have the same issue.
Re: Do statin drugs mimic a vitamin?
Posted: Sat Jan 26, 2008 9:49 am
by J.Lilinoe
Oh please, I hope that statin drugs don't mimic any vitamin. How dreadful.
Re: Do statin drugs mimic a vitamin?
Posted: Sat Jan 26, 2008 10:41 am
by Ralph Lotz
Re: Do statin drugs mimic a vitamin?
Posted: Sat Jan 26, 2008 12:41 pm
by Seymore Spectacles
I don't think the
vitamin D mimic theory holds water. If you look at the vitamin D table (found by following Ralph's link), you'll see that the patients receiving a
placebo had a much greater increase in vitamin D levels than did the statin users.
This alone seems to suggest the exact opposite of what is being suggested in that part of the article.
Drug Status
Took drug or inactive placebo
Vitamin D level (nanomole/Liter of blood)
No statin
Active 65.9
Placebo 38.4
On statin
Active 74.0
Placebo 50.0
Source: American Journal Cardiology 2007 October 15; 100(8): 1329.
Note that the increase for statin users went from 65.9 to 74. I believe this is about an 11% increase.
The increase in the placebo users went from 38.4 to 50. I believe this is about a 23% increase
Re: Do statin drugs mimic a vitamin?
Posted: Mon Jan 28, 2008 8:48 pm
by Ralph Lotz
Re: Do statin drugs mimic a vitamin?
Posted: Mon Jan 28, 2008 8:54 pm
by J.Lilinoe
Do vitamins mimic the hazardous side effects of statins?
Most likely no, so I hope the researcher's work was thorough.
Re: Do statin drugs mimic a vitamin?
Posted: Mon Jan 28, 2008 9:22 pm
by Ralph Lotz