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A Prediction of Linus Pauling's Theory?

Posted: Sat Mar 20, 2010 7:13 pm
by chimp
http://abcnews.go.com/Health/HeartDisea ... d=10140233



A group of elite long-distance runners had less body fat, better cholesterol and blood lipid profiles, and better heart rates than people being tested for cardiac disease. Paradoxically, however, the runners had more calcified plaque in their heart arteries, according to a study reported this week.



Re: A Prediction of Linus Pauling's Theory?

Posted: Sun Mar 21, 2010 3:24 am
by ofonorow
Excellent find, and you are right, the Unified Theory would predict that elevated mechanical stress would increase the activity of the arterial repair mechanism. Lp(a) would be an interesting data point..
The reasons for the high-calcified plaque readings among hard-core athletes are elusive, "but the [runners'] favorable factors may be counterbalanced by metabolic and mechanical factors that enhance coronary plaque growth," suggested Dr. Jonathan Schwartz of the University of Colorado Health Science Center in Denver, lead author of the study and son of Robert Schwartz.


I may try to contact Dr. Schwartz and suggest he try giving the athletes Pauling's recommended vitamin C and lysine (and vitamin K for the plaque) for one or two months, and then rerunning the CT-angiography scans. (Although I have done this often enough in the past to know it is probably a waste of time.)

Re: A Prediction of Linus Pauling's Theory?

Posted: Mon Mar 22, 2010 7:35 pm
by Ralph Lotz
Dr. Joe Prendergast completely reversed his calcified arteries with 5 grams of L-Arginine daily.
http://vimeo.com/4847022

Listen to Dr. Joe's interview here with my friend and former colleague at Source Naturals, David Stouder:

http://www.thevitaminshelf.net/audio/tvs7-17-08se.mp3

Re: A Prediction of Linus Pauling's Theory?

Posted: Tue Mar 23, 2010 4:19 am
by ofonorow
Ralph, the only question I have is if arginine was the only supplement he was taking? The video did not make that clear. Do we know he didn't try vitamin C and lysine, for example?

Re: A Prediction of Linus Pauling's Theory?

Posted: Tue Mar 23, 2010 5:57 am
by VanCanada
This is based on the nitric oxide pathway which has been well researched and has won two scientists the Nobel Prize.

I first heard about M.D. endocrinologist Dr. Joseph Prendergast on a radio show from the San Francisco area called The Vitamin Shelf with host David Stouder. I find them fascinating and have listened to all episodes featuring Dr. Prendergast at least twice. He has prescribed daily doses of fifty thousand IU's of Vitamin D since 1964 (it was prescribed for osteomalacia back then)!

The radio shows describe some of the common protocols that Dr. Prendergast uses with the patients who see him. He often has new patients take fifty thousand IU's daily for thirty to sixty days and then he tests their blood levels. Then they will reduce daily intake to between five and twenty thousand IU's after that to maintain a target blood level of between "100 and 200". I'm pretty sure he's talking about ng/mL although he never does specify. In the March 17, 2009 show he says that if patients remain on a high intake for more than 200 days that their blood levels will peak at that time and then actually begin to decline until about day 365.
David Stouder's radio shows are archived on the internet as freely downloadable mp3 files if you're interested. The first seven listed below feature Dr. Prendergast as a guest and the eighth features perhaps the world's foremost authority on Vitamin D toxicity:

(a) posted to website on May 2, 2007
http://www.thevitaminshelf.net/audio/drjoe2.mp3

(b) June 6, 2007
http://www.thevitaminshelf.net/audio/L-Arg-VitD.mp3

(c) March 9, 2008
http://www.thehealthwarrior.net/mp3/THW-3-09-08.mp3

(d) July 20, 2008
http://www.thevitaminshelf.net/audio/tvs7-17-08se.mp3

(e) Nov. 9, 2008
http://www.thehealthwarrior.net/mp3/THW-11-09-08.mp3

(f) Feb. 23, 2009
http://www.thevitaminshelf.net/audio/tvs2-18-09a.mp3

(g) March 17, 2009
http://www.thehealthwarrior.net/mp3/THW-3-17-09.mp3

(h) This Jan. 17, 2009 interview with University of Toronto researcher Rheinhold Vieth is also very good.
http://www.thevitaminshelf.net/audio/tvs12-22-08.mp3

Dr. Prendergast's contact info is as follows:

Endocrine Metabolic Medical Center
350 Cambridge Avenue, Suite 250
Palo Alto, CA 94306-1575
Telephone: (650) 566-9810
Fax: (650) 566-9825

email: office@endocrinemetabolic.com
website: http://www.endocrinemetabolic.com/
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Re: A Prediction of Linus Pauling's Theory?

Posted: Wed Mar 24, 2010 11:55 pm
by Lone Dog
Looking around on the internet, it seems there are quite a few advocates of L-Arginine, and L-Citrulline (as a precursor of L-Arginine) as creators of NO, which they feel may work to clear arteries. Here's a link which points to a few books which might be useful.

http://www.forbiddenknowledge.info/arginine.html

Dr Prendergast advocates D3 in large amounts, 50,000iu, so I wonder if he was using this during the years he apparently reversed his atherosclerosis, and it helped with calcified plaque reversal.

In my opinion, if 5G of L-Arginine per day is going to increase blood flow, it could be a useful adjuct to the pauling therapy to help get the C and Lysine into places where they couldn't get before.