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drtom wrote:This article discusses the fact that Vitamin C supplementation does not affect inflammatory markers (meaning does not lower them):
https://www.ncbi.nlm.nih.gov/pubmed/18427418
drtom wrote:More fundamental than collagen repair is to stop the inflammation that causes (or is a huge factor in developing) coronary arterial disease in the first place
jimmylesante wrote:Going carnivore may in the short term work but in itself may cause inflammation and other damage without the protective effects of fruit and vegetables.
drtom wrote:Vitamin C supplementation in much greater doses than found in the diet does not seem to hurt in part because Vitamin C rapidly disappears from the blood stream (is used up).
The patients had been encouraged as part of their treatment to supplement AA. Self-reported daily intake varied from 0 to 20 g/day. The plasma AA levels ranged from 11.4 to 517 µmol/L and correlated well with the reported intake. Regression analysis of their GHb and plasma AA values showed a statistically significant inverse association (eg, each 30 µmol/L increase in plasma AA concentration resulted in a decrease of 0.1 in GHb).
drtom wrote:What I was trying to emphasize is that the CAUSE of much of the adverse inflammation that is responsible for so many of our diseases is from too much glucose being consumed too many times a day, whether by eating too much glucose (sugar) or food substances that are rapidly converted to glucose (starchy and refined carbs, grains, etc.).
What factors can lead to the situation where damage outstrips repair? First, we need to look at those factors that increase the rate of damage. There are many, many, things that can do this. Here is a list. It is non-exhaustive, it is in no particular order, but it may give you some idea of the number of things that can cause CVD, by accelerating endothelial damage:
Smoking
Systemic Lupus Erythematosus
Use of oral steroids
Cushing’s disease
Kawasaki’s disease
Rheumatoid arthritis
High blood pressure
Omeprazole
Avastin
Thalidomide
Air pollution
Lead (the heavy metal)
Mercury
High blood sugar
Erythema nodosum
Rheumatoid arthritis
Low albumin
Acute physical stress
Acute mental stress
Chronic negative mental stress
Chronic Kidney Disease
Dehydration
Sickle cell disease
Malaria
Diabetes/high blood sugar level
Bacterial infections
Viral infections
Vitamin C deficiency
Vitamin B deficiency
High homocysteine level
Chronic kidney disease
Acute renal failure
Cocaine
Angiotensin II
Activation of the renin aldosterone angiotensin system (RAAS) etc.
Blimey, yes, that list was just off the top of my head, I could get you another fifty without much effort. And no, I did not just make it up. I have studied every single one of those factors, and many more, in exhaustive detail. The extent of how many factors there are, should not really come as a surprise to anyone, but it usually does.
Nick thought quite differently, believing that each of us is unique not only in height, weight and shoe size, but also in terms of dietary and nutritional needs. He relied on not one but ten basic diets, ranging from the nearly purely vegetarian to mostly red meat, with the fat, throughout the day. His predecessor Dr. Kelley spent years of his professional life insisting that one size doesn’t fit all, that each of us is biochemically and nutritionally unique and each of us requires a diet designed for our specific metabolic needs.
Ironically, when dentist Dr. Kelley first began treating patients with other than dental disease in the late 1950s and early 1960s, he believed that for optimal health humans should eat vegetarian, period. However nice the theory might have sounded, in practice he discovered that vegetarianism worked only for occasional patients, and that many actually worsened eating this way. Through a process of trial and error, he learned that though some of his patients did well with a plant based diet, to his astonishment many did best when they ate red meat and only minimal vegetables and fruits, and some thrived when he prescribed a diet allowing a variety of both plant and animal based foods.
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