IV/C May Prevent Kidney Injury from Antibiotic

Physician Reference and discussion of the methods, protocols and effects of intravenous vitamin C (versus oral or liposomal).

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OxC
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IV/C May Prevent Kidney Injury from Antibiotic

Post Number:#1  Post by OxC » Mon Oct 05, 2015 2:29 pm

According to Wiki, "colistin (polymyxin E) is a polymyxin antibiotic...Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter."

A new study suggests that IV/C given at the same time patients are given this antibiotic helps prevent the Acute Kidney Injury (AKI) that it can cause.
In severely ill patients receiving colistin according to a PK/PD-driven dosing approach, baseline renal impairment and older age strongly predict AKI occurrence, but concomitant administration of ascorbic acid markedly reduces AKI risk, allowing safer use of colistin.

Colistin-associated Acute Kidney Injury in Severely Ill Patients: A Step Toward a Better Renal Care? A Prospective Cohort Study. Clin Infect Dis. (2015) doi: 10.1093/cid/civ717 First published online: September 9, 2015
Douglas Q. Kitt, founder of ReCverin LLC, sellers of stabilized dehydroascorbic acid solutions.

eDOC
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Re: IV/C May Prevent Kidney Injury from Antibiotic

Post Number:#2  Post by eDOC » Tue Oct 06, 2015 1:51 pm

Not IVC but GSH.
Rookie, rusty, sub average doc but one that gives results!


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