Relative Died from Sepsis - Want to be able to give IV/C at home

Physician Reference and discussion of the methods, protocols and effects of intravenous vitamin C (versus oral or liposomal).

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ofonorow
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Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#1  Post by ofonorow » Wed Nov 30, 2016 12:02 pm

Dear Owen

A relative of mine died from sepsis.

While in ICU his family asked for vitamin C iv. Surprisingly they agreed:
"Usually we give this in the burn unit -3 x 10 gram-, but okay, it is not expensive so I can do that. But max 3 x 10 gram, and if the kidneys are bad, I will give 10 gram once only."

An hour later they said that they could start the iv C only next day because the pharmacy was closed (it was evening and weekend).

Another hour later the patient died.

My question: I don't want this ever to happen again and have vitamin C for iv ready at home in case of emergency. It should look professionally prepared, otherwise the doctor will refuse to use it - which is understandable.

I live in Europe so I guess you don't have any addresses where I can get this.

But I found on your website that it should be compounded by the pharmacy.
http://vitamincfoundation.org/ivc/

Could you please give me the compounding instructions?

Thank you


The rules in Europe may be different, but in the USA, the answer is to find a hospital willing to approve IV/C by adding it to the pharmacy. This is discussed on Dr. Saul's Doctoryourself.com web site. (In your case, the pharmacy in a hospital was closed??)

We stress that sterile vitamin C is available in the USA for injection from compounding pharmacies.

However, it is true that more and more alt. docs are following in the footsteps of of the late Dr. Robert Cathcart III, MD, and using off-the-shelf sodium ascorbate to make IV/C solutions for intravenous infusion and injection (per the link you provided). Cathcart believed that a 50/50 sodium ascorbate/sterile water solution is self-sterilizing.
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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#2  Post by ofonorow » Wed Nov 30, 2016 12:06 pm

Your link of ours should be updated! Here is a better one for now
http://www.vitamincfoundation.org/pdfs/civprep.pdf
Owen R. Fonorow
HeartCURE.Info
American Scientist's Invention Could Prevent 350,000 Heart Bypass Operations a year

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#3  Post by dectiri » Tue Mar 21, 2017 12:40 pm

Like you I have searched for alternatives that are ortho and human-friendly to administer... IV-C is beyond my abilities I believe but there is another way to use C that would be our own choice... why? because I found a report of a doctor using hyperbaric o2 and his protocol was simple and comfort-providing... he had the nurse-monitoring set so that if the patient's heart rate rose to 120bpm then they would put the patient into the hbot chamber and do a treatment... the relief for the patient's heart and immune system and brain was clear and the patients given that protocol all survived.

We are aware that hospitals here that have hbot chambers all use the mongo $250grand models like the Secrest but we've also seen that in a recent DOD (traumatic brain injury) study on the use of hbot vs the usual standard of drugs and talk, they used the little portable chambers (about the price of a pickup truck with some used available even lower) as the PLACEBO....

well wouldn't you know, those who did the 'placebo' hbot (like used by athletes) did as well as the big secrests AND both beat the standard drug approach... so the published research advertised that don't bother with hbot b/c "it didn't do any better than placebo !!" imagine such a farce and open fraud... yet the media lapped it up... infuriating!

so what about europe... well I do know that in Europe, the regulators were not as successful at hampering public access to small 'placebo'-type models with levels of hyperbaric pressure like the 1.3ATA used in the USA likely for the 'placebo'... chambers in the EU can do 1.5ATA.. and as I recall, the MS patients of Britain banded together and set up their own network of sites where they charge only $15 or somesuch for a treatment when I read last... so there must be a decent market in used chambers..

Plus for pneumonia patients (IIRC from searching their research, quite extensive, may even have more sepsis data), the Russians added antioxidents, like our own C orally if possible... and anyone feeling poorly should start immediately upping their dose-levels of C... agreed? especially with Irwin Stone's research showing that the levels of the C (ascorbic acid vs DHAA) are predictive of survival of the patient IF THE RATIO IS OVER 1.. imagine that.. taking that extra C pushes the numerator up, automatically making the ratio higher and survival more likely.... and even better, with more C then the DHAA is *likely* less (because DHAA is the total ascorbic acid minus the 'reduced' C that you are adding with your dosing)...

and once you start reading up on hbot you will see that your anticipated chamber has so many other benefits for your family's idea of your own recovery room in your own home that you'll wonder how it's possible that you would ever think it would be unneeded except for a sepsis emergency... broken bones heal better, stroke patients heal, heart attacks can be interrupted, child birth is wholly different and safer, drowning and carbon monoxide... all so compatible with our reading of C and such antioxidants...

And no I don't own stock or sell these favored chambers... we however do have a pair that we use for our cat rescue work and use them regularly, such as post surgery... or pre-surgery even is listed in the benefits..... just like C

hope this helps as we are advocates of using IV-C at the veterinary hospitals BUT JUST DISCOVERED THAT YOU SHOULD **NEVER** USE IT **DURING** SURGERY... NEVER... Dr Thomas Levy, when we talked to him about the results we had seen said he hoped the kittens would forgive us for trying to improve their safety and healing..... only during surgical removal of mercury amalgams in HUMANS would he venture as an exception.. ttyl..

and btw, those kittens are doing well enough, just seemed more *aware* of their trauma than usual.. next time, oral C in the buildup period before surgery (as always), maybe a squirt when we drop them off with instructions to the staff to return our kittens to the carrier (now to be equipped with north-up-magnetic floor to immediately accelerate healing) as soon as they are off the operating table like the staff does for ferals (not risking handling a frightened feral any more than needed as that can be alarmingly disruptive to hospital 'serenity')....

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#4  Post by OxC » Wed Mar 22, 2017 3:09 pm

A relative of mine died from sepsis...
My question: I don't want this ever to happen again and have vitamin C for iv ready at home in case of emergency. It should look professionally prepared, otherwise the doctor will refuse to use it - which is understandable.

While I can't suggest an answer to your question, it may be comforting to know that huge progress is being made in mainstream medicine in regard to the use of IVC in sepsis and Acute Respiratory Stress Syndrome (ARDS). I think it is possible that it may become standard-of-care within just another year or two, and perhaps we won't have to worry about the possibility that the intensive care unit doesn't have it on hand:

http://www.townsendletter.com/Oct2015/sepsis1015_2.html
https://kwikermedical.com/news/2016/6/3 ... onferencei
https://www.hindawi.com/journals/cricc/2016/8560871/
https://clinicaltrials.gov/ct2/show/record/NCT02734147
https://clinicaltrials.gov/ct2/show/results/NCT01434121
https://clinicaltrials.gov/ct2/show/results/NCT02106975
Douglas Q. Kitt, founder of ReCverin LLC, sellers of stabilized dehydroascorbic acid solutions.

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#5  Post by OxC » Thu Mar 23, 2017 3:20 pm

Strangely enough, this was published just this morning:
Doctor Turns Up Possible Treatment For Deadly Sepsis
Douglas Q. Kitt, founder of ReCverin LLC, sellers of stabilized dehydroascorbic acid solutions.

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#6  Post by OxC » Fri Mar 24, 2017 10:55 am

OxC wrote:
A relative of mine died from sepsis...
My question: I don't want this ever to happen again and have vitamin C for iv ready at home in case of emergency. It should look professionally prepared, otherwise the doctor will refuse to use it - which is understandable.

While I can't suggest an answer to your question, it may be comforting to know that huge progress is being made in mainstream medicine in regard to the use of IVC in sepsis and Acute Respiratory Distress Syndrome (ARDS). I think it is possible that it may become standard-of-care within just another year or two, and perhaps we won't have to worry about the possibility that the intensive care unit doesn't have it on hand:

http://www.townsendletter.com/Oct2015/sepsis1015_2.html
https://kwikermedical.com/news/2016/6/3 ... onferencei
https://www.hindawi.com/journals/cricc/2016/8560871/
https://clinicaltrials.gov/ct2/show/record/NCT02734147
https://clinicaltrials.gov/ct2/show/results/NCT01434121
https://clinicaltrials.gov/ct2/show/results/NCT02106975
Douglas Q. Kitt, founder of ReCverin LLC, sellers of stabilized dehydroascorbic acid solutions.

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#7  Post by OxC » Fri Mar 24, 2017 11:24 am

OxC wrote:http://www.townsendletter.com/Oct2015/sepsis1015_2.html

In this Townsend Letter interview, Dr. Fowler was asked about the mechanisms-of-action…how vitamin C might work in treating sepsis. He said,
My research colleagues and I have extensively documented the potent effects of AA. Importantly, AA "downregulates" or attenuates the extent of the inflammatory response that occurs in sepsis. Critical pro-inflammatory proteins that are released into the bloodstream following the onset of sepsis are very significantly attenuated. AA does this by blocking the activation of an important transcription factor (nuclear factor-kappa B) (NF-κB) that drives the "expression" of the genes which lead to surges of the various inflammatory proteins in the bloodstream after sepsis starts.


But in this study Vitamin C Is a Kinase Inhibitor: Dehydroascorbic Acid Inhibits IκBα Kinase β, the authors said,
Acting as an antioxidant, ascorbic acid (AA) donates two electrons and becomes oxidized to dehydroascorbic acid (DHA). We discovered that DHA directly inhibits IκBα kinase β (IKKβ) and IKKα enzymatic activity in vitro, whereas AA did not have this effect. When cells were loaded with AA and induced to generate DHA by oxidative stress in cells expressing a constitutive active IKKβ, NF-κB activation was inhibited. Our results identify a dual molecular action of vitamin C in signal transduction and provide a direct linkage between the redox state of vitamin C and NF-κB signaling events. AA quenches ROS intermediates involved in the activation of NF-κB and is oxidized to DHA, which directly inhibits IKKβ and IKKα enzymatic activity.


So it appears that the benefits of IVC in sepsis are in part due to the unique effects of the DHAA created when the AA becomes oxidized. This leads me to wonder if the infusion of a mixture of AA and DHAA might be more effective than AA alone, by increasing the concentration of one of the active components.
Douglas Q. Kitt, founder of ReCverin LLC, sellers of stabilized dehydroascorbic acid solutions.

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Re: Relative Died from Sepsis - Want to be able to give IV/C at home

Post Number:#8  Post by dectiri » Tue Dec 01, 2020 11:44 am

"Could you please give me the compounding instructions?"

When we advocated trying injectable c for some of our cats in the rescue, the veterinarian only wrote 'preservative-free' as the crucial piece to guide the pharmacist... We had the ampule [quantity and dose] as the remaining piece... The pharmacist made a phone call to some central recipe resource and then told us it would take 24hours, so we should come back the next day, to purchase, and take to the veterinarian for administration....

Totally against sane needs....

Off the shelf will have preservatives -- likely EDTA and some 'paraben' type stuff....
†ake your pick.......

In order to have a supply of preservative-free injectible C in hand at the hospital, they would have to keep it either FROSEN [45 day limit] or REFRIGERATED [1 week limit]...

WE NEED TO GET TO THE STATE WHERE THE HOSPITALS ARE USING THIS PRESERVATIVE-FREE IVC SO REGULARLY THAT THEY'D EASILY HAVE THE SUPPLIES HANDY FOR THE DEMAND, WITHIN THOSE PRESERVATIVE-FREE LIMITS....

NOT THAT CLOSE YET.... courtesy of the FDA until the damn swamp gets drained on the medical side.... ttyl... sorry for the bad news


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