Professor Ian Brighthope on IV Vit C

Physician Reference and discussion of the methods, protocols and effects of intravenous vitamin C (versus oral or liposomal).

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majkinetor
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Professor Ian Brighthope on IV Vit C

Post Number:#1  Post by majkinetor » Thu Jun 07, 2012 8:47 pm

http://goo.gl/V0c2m

Intravenous Ascorbic Acid in the Treatment of Influenza: Lack of Evidence or Incontrovertible Ignorance?

Professor Ian Brighthope, MB.BS., D.Ag.Sci., FACNEM, FACHM
Australasian College of Nutritional and Environmental Medicine.Volume 30 No.2


It is time that the medical orthodoxy embraced the use of intravenous vitamin C to save lives and improve prognoses. Patients are dying as a result of the failure of our medical system to use IVC. As researcher Mark Levine has observed, after fifty years of study and debate, the use of intravenous ascorbic acid remains ‘controversial, colourful and emotional,’ it being forced into ‘culs de sac, regressions and periods of blindness and amnesia’, by its opponents. As one such opponent, Dr David Ghaller, a senior intensive care specialist in New Zealand stated in the same 60 minutes story, “We as a group believe it is harmful, and in this setting of critical illness, potential for harm outweighs any therapeutic benefit.” In light of the actual evidence, anecdotal or otherwise, such a statement belies belief. It doesn’t work because they haven’t tried it. It doesn’t work because they have been told it doesn’t work, it is a major myth in the medical profession that needs to be debunked once and for all.

ofonorow
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Re: Professor Ian Brighthope on IV Vit C

Post Number:#2  Post by ofonorow » Fri Jun 08, 2012 3:07 am

Unfortunately, as long as IV/C has the potential to bankrupt hospitals, it doesn't matter how well it works.

And for those still reading , our own (unintentional) research has unequivocally demonstrated that not all IV/C are created equal!

There are basicallytwo major forms of IV/C - the "mild" and currently only commercial form (from Bioniche) is buffered ascorbic acid. The product is vitamin C, and can flush toxins, say after dental work.

In my opinion, the pH is probably too low to take the commercial I/Vs continuously w/out vein damage.

On the other hand, the I/Vs developed and used by the late Dr. Robert Cathcart, III, MD, are not only safe (proper pH) but perhaps an order of magnitude more effective! (My current alt. doc didn't believe there could be much difference, but now is engaging on a side-project to have both analyzed to identify the difference so that he can write a paper.) THE DIFFERENCE IS THAT DRAMATIC. The so-called Herxheimer reaction is the give away. If you are looking for maximum therapeutic effect, the IV must be sodium ascorbate mixed per Cathcart's instructions PDF: http://www.vitamincfoundation.org/ivc/civprep.pdf VIDEO: http://www.youtube.com/watch?v=Zgi-7xPrCAg

And now you can get the Cathcart style sodium ascorbate for IV from a few compounding pharmacies (with a prescription).
Owen R. Fonorow
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American Scientist's Invention Could Prevent 350,000 Heart Bypass Operations a year

majkinetor
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Re: Professor Ian Brighthope on IV Vit C

Post Number:#3  Post by majkinetor » Fri Jun 08, 2012 4:54 am

What is the reason for hypoglicemia, I wonder ... ? Vitamin C boosts insulin release ?

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Re: Professor Ian Brighthope on IV Vit C

Post Number:#4  Post by ofonorow » Fri Jun 08, 2012 5:51 am

Good question about insulin - as Pauling would say, "What do we know?"

Alt docs familiar with IV/C actually GIVE insulin with the C to promote more vitamin C entry into cells. Usually towards the end of a course of IV/C treatment.

Any study that shows vitamin C raises serum insulin would be of interest. (Pauling/Stone did not write about this,
to my knowledge, so I doubt the effect (vitamin C promotes insulin secretion) is large. But I am willing to learn.)

Depends on the definition of "hypoglycemia." If functional, the patient craves sweets, perhaps it is due to competition with C in the plasma, and less glucose reaches cells. If the blood plasma is actually become depleted of glucose then it may be something else.

For example, adrenal fatigue causes hypoglycemia because cortisol (glucorticoids) have an effect on the liver, creating glucose during sleep and periods of fasting. When they are not present, the liver is not stimulated to make glucose. So high vitamin C may be somehow interferring with this glucose regulating mechanism.
Owen R. Fonorow
HeartCURE.Info
American Scientist's Invention Could Prevent 350,000 Heart Bypass Operations a year

majkinetor
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Re: Professor Ian Brighthope on IV Vit C

Post Number:#5  Post by majkinetor » Fri Jun 08, 2012 7:47 am

Ah yes, that is one mechanism, vitamin C probably make adrenals work better (which is also why I doubt you have malfunctioning adrenals).

AFAIK, C doesn't influence insulin much, although there are some papers around that show it is necessary for insulin release (at least in scorbutic g. pigs) and some papers that show it blocks insulin release.

Wells, W W, C Z Dou, L N Dybas, C H Jung, H L Kalbach, and D P Xu. “Ascorbic Acid Is Essential for the Release of Insulin from Scorbutic Guinea Pig Pancreatic Islets.” Proceedings of the National Academy of Sciences of the United States of America 92, no. 25 (December 5, 1995): 11869–11873. http://www.ncbi.nlm.nih.gov/pubmed/8524865.

Bergsten, P, A S Moura, I Atwater, and M Levine. “Ascorbic Acid and Insulin Secretion in Pancreatic Islets.” The Journal of Biological Chemistry 269, no. 2 (January 14, 1994): 1041–1045. http://www.ncbi.nlm.nih.gov/pubmed/8288558.

Johnston, C S, and M F Yen. “Megadose of Vitamin C Delays Insulin Response to a Glucose Challenge in Normoglycemic Adults.” The American Journal of Clinical Nutrition 60, no. 5 (November 1994): 735–738. http://www.ncbi.nlm.nih.gov/pubmed/7942581.

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Re: Professor Ian Brighthope on IV Vit C

Post Number:#6  Post by majkinetor » Fri Jun 08, 2012 8:58 am

Cunningham, J J. “The Glucose/insulin System and Vitamin C: Implications in Insulin-dependent Diabetes Mellitus.” Journal of the American College of Nutrition 17, no. 2 (April 1998): 105–108. http://www.ncbi.nlm.nih.gov/pubmed/9550452.

The recent observation of a clear late-phase insulin release
following an intravenous infusion of ASC [12] could explain
the variability seen in tissue ASC stores in IDDM (Fig. 1) if an
insulin release is important for cellular ASC uptake. That is,
since the exogenous replacement of insulin for IDDM occurs in
discrete episodes that may or may not be closely coupled to
dietary vitamin C intake, some individuals with IDDM may be
disadvantaged by the absence of insulin-stimulated transport in
response to an increase in plasma ASC

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Re: Professor Ian Brighthope on IV Vit C

Post Number:#7  Post by majkinetor » Fri Jun 08, 2012 10:32 pm

Paolisso, G, A D’Amore, V Balbi, C Volpe, D Galzerano, D Giugliano, S Sgambato, M Varricchio, and F D’Onofrio. “Plasma Vitamin C Affects Glucose Homeostasis in Healthy Subjects and in Non-insulin-dependent Diabetics.” The American Journal of Physiology 266, no. 2 Pt 1 (February 1994): E261–268. http://www.ncbi.nlm.nih.gov/pubmed/8141285.


At the highest vitamin C infusion rate (0.9 mmol/
min) the increase in plasma vitamin C levels did not affect
B cell response to glucose, but it improved Conard’s K values
and whole body glucose disposal in healthy subjects and in
diabetic patients. In both groups of subjects vitamin C-mediated increase in insulin action was mainly due to an
improvement in nonoxidative glucose metabolism. After fast­
ing, plasma vitamin C levels correlated with basal whole body
glucose disposal (r = —0.44, P < 0.05; n= 20). After vitamin
C infusion, percent change in plasma vitamin C level corre­
lated with the percent decline in membrane microviscosity
(r = 0.53, P < 0.01; n - 20) and increase in whole body
glucose disposal (r = 0.63, P < 0.003; n= 20). In conclusion,
plasma vitamin C levels seem to play a role in the modulation
o f insulin action in aged healthy and diabetic subjects


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