https://www.medicalnewstoday.com/articles/320848.php
The TBK-1 enzyme is a burn fat/store fat switch. When inhibited, fat is burned.
Its interesting because the researchers found an old Asthma drug (developed in Japan, and no longer available in the USA) called amlexanox inhibits TBK-1, and thus induces fat burning! The drug is an anti-inflammatory drug, and in theory, you could take it while you needed to burn fat, and then stop
Wiki says discontinued in the USA https://en.wikipedia.org/wiki/Amlexanox and has a tradename of Aphthasol. The wiki said the drugs was administered topically.
Strange that the drug would be taken off the market.. I remember something like this when vitamin K2 was found to be anti-cancer, it to was removed from the marketplace.
Another story
https://www.sciencedaily.com/releases/2018/02/180208141245.htm that discusses amlexanox.
Canker sore drug helps mice lose weight without diet, exercise
https://www.cnn.com/2013/02/10/health/mice-weight-loss-drug/index.html
nature medicine journal article
https://www.nature.com/articles/nm.3082
During the search, happened to notice this news that there is now a way to triple the effectiveness of Lipase, the enzyme that breaks down fats so they can be metabolized... For future reference.
https://www.forbes.com/sites/melaniehaiken/2012/08/24/big-weight-loss-news-scientists-discover-switch-that-turns-on-fat-burning-enzymes/#2f48b2bd140a