Moderator: ofonorow
bbtri wrote:On the H Pylori thing I've read that it can make GERD less likely because the bacteria lower stomach acid.
methyl prednisolone if im not mistakes is a corticosteroid so it will not only reduce inflammation but also hinder the immune response making for a possible interesting intestinal reaction
ofonorow wrote:He he he. Sorry, I hear this all the time from M.Ds. Fortunately the truth is out there. For anyone who believes this (that corticosteroids hinder immunity, as most doctors I speak with apparently do) you might consider reading William Mck Jefferies SAFE USES OF CORTISOL, 3rd Edition. Fantastic book (at least 2 me, because it completely explained two week long stays in intensive care - that completely fooled the 10+ specialist assigned to my "case.").
ofonorow wrote:What was the "high dose" exitium - and why were you on a high dosage? Any more than 8-10 mg of prednisone is unsafe for more than a short time - sort of like producing your own elevated cortisol under chronic stress.
The recommended safe dosage - extrapolating from the hydrocortisone discussed in the Jefferies' book - is about half normal adrenal output, or 4 mg.
8-10 mg (prednisone) equals "normal" unstressed daily cortisol output. (Apparently they used to remove adrenal glands from cancer/breast cancer patients, and this is how they determined the "replacement" dosages in the 1950s.)
The message in Jefferies's book is that if a doctor prescribes in the safe range, the adrenal output is reduced, resting the adrenals. (The output of cortisol is tightly controlled by the brain, and is not additive.)
You don't want to stay on full replacement (8-10 mg) for too long as the adrenals would then switch off for lack of work.
Any more than 8-10 mg is unsafe at any speed .. err any real length of time.
But 1, 2 3 or 4 is supposed to be safe in that the adrenals only have to output 1/2 their usual, leaving spare capacity when you do have a stress to combat.
I am curious how much you were taking and why.
ofonorow wrote:Exitium, I was thinking about the dosage you took (50 mg) for an extended length of time (6 months) , and if you care to relate what happened, that would be interesting. I suspect your blood sugar went through the roof, and if not, how did they control it?
Needless to say I felt pretty good for the first week or so, then bloated up nicely, thirsty all the time and was in the bathroom all the time, seemed to get a cold every other week etc.
ofonorow wrote:[color=#000080][b]Bloating is common. Thirsty all the time indicates an elevation in blood sugar - lucky you didn't go into a coma. I have also been told that by turning off your adrenals (as this must have) you become dependent.
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