Evaluation of the Effect of Topically Applied Melatonin and Vitamin C in the Non-surgical Treatment of Chronic Periodont

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Evaluation of the Effect of Topically Applied Melatonin and Vitamin C in the Non-surgical Treatment of Chronic Periodontitis: A Triple-Blind Randomized Clinical Trial

https://www.cureus.com/articles/325009- ... l-trial#!/

Conclusions

Based on the results of the current study, treatment with melatonin and vitamin C as an adjunct to SRP may improve periodontal indices (PD, CAL, and GI) compared to SRP alone. Combined use of these two locally delivered drugs showed better improvement in the long term.