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The 4-year incidence of PD was 54 per 100,000 person-years for whites, 23 per 100,000 person-years for African-Americans and 40 per 100,000 person-years for Latinos. This translates to a 4-year cumulative risk of PD that was 0.18%.
Alzheimer's, MS, Parkinson's, ... –
Effective means in neurodegenerative diseases Part 1
Newsletter Contribution by Dominik Dietz
To the YouTube video from
Dr. Hartmut Fischer
In view of the advancing developments in the field of neurodegenerative diseases, including multiple sclerosis, Parkinson's disease, Alzheimer's disease/denz, ALS and polyneuropathy, this newsletter is dedicated to a comprehensive presentation of the various health toolbox agents. These funds, which have already been discussed in previous editions, are now presented in summary to provide a sound overview of their potential in supporting and coping with these diseases.
Proven agents include DMSO, medicinal plants tinctures, choline, galactose, melatonin, GABA, lithium chloride, electrolyte compound, acetylcysteine, 5-HMF, theophylline, N-acetyl-glucosamine and alpha-lipoic acid.
Although the focus of this newsletter is on these specific means, it is important to emphasize that a holistic treatment strategy for neurodegenerative diseases should also take life, nutrition and thinking habits into account. These include optimal diets, detoxification strategies, protection against electrosmog and the promotion of mental and emotional health. To deepen these aspects, a podcast and video course on holistic health/isupplement available on our website at , which provides the basics and a good overview of the most important pillars of holistic health.
However, in order to keep the scope of this newsletter manageable, we focus on the therapeutic means below.
Basic basic care for the prevention and treatment of neurodegenerative diseases
Before we focus on the special health toolkits to cope with neurodegenerative diseases, it is essential to ensure sound basic care. This serves as a foundation for the prevention and management of such conditions.
Essential substances for optimal support include:
Vitamin D3, K2 and Magnesium: Vitamin D3 is crucial for neuronal health and influences over 2000 genes that are closely related to nerve and brain function. A lack of this vitamin can trigger neurodegenerative symptoms such as muscle tremors and walking difficulties. Vitamin K2 complements the effect of D3 by regulating the distribution of calcium and ensuring that it is stored in the bones – a process that is crucial for cognitive function and avoidance of vascular deposits. Magnesium, which is crucial for the activation of vitamin D3 and K2, should ideally be used transdermal to maximize the absorption rate. This method is particularly effective because it increases the bioavailability of magnesium and offers systemic benefits. This trio should be taken (along) together during a high-fat meal to maximise their health benefits, especially for people who are prone to or are already affected by neurodegenerative conditions.
Vitamin B Complex : Vitamin B complex is indispensable for the prevention and management of neurodegenerative diseases, as it directly supports neuronal health. The group of B vitamins includes essential nutrients that are crucial for a variety of metabolic and neurotransmitter functions, with each vitamin fulfils specific tasks in the human body. A lack of one of these vitamins can have far-reaching consequences for brain health, such as cognitive impairments and increased susceptibility to neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Particularly important are vitamins B6, B9 (folic acid) and B12, which directly influence the function and repair of nerve cells and contribute to the synthesis of DNA and RNA. An adequate supply of vitamin B through supplementation is therefore essential to protect the nervous system and maintain mental performance. Natural and bioavailable forms of vitamin B complex are preferable, as these can be better absorbed and utilized by the body.
Vitamin B12 : This essential vitamin plays a crucial role in the prevention and treatment of neurodegenerative diseases. It not only supports nerve integrity by setting up and maintaining myelin sheaths, but also promotes neuronal communication and neurotransmitter function. Sufficient B12 level can protect against symptoms such as memory loss, muscle weakness and sensory disorders, which are often associated with conditions such as MS and Alzheimer's. Vitamin B12 can be absorbed both orally and per injection. Drops or lozenges are suitable for oral absorption, as they allow rapid absorption through the oral mucosa. Intramuscular injection is suitable for intake disorders due to gastrointestinal problems or other absorption disorders. This method ensures a direct and rapid absorption of the vitamin into the bloodstream, which is particularly helpful for acute deficiencies or serious neurological symptoms.
Omega-3 fatty acids (algae oil): algae oil, obtained from the microalgae Schizochytrium sp., is an excellent source of essential long-chain omega-3 fatty acids, especially EPA and DHA. These fatty acids are crucial for neuronal integrity, directly support the brain and nervous system and play a central role in the prevention and treatment of neurodegenerative diseases. In addition, algae oil promotes the health of the cardiovascular system due to its anti-inflammatory properties. As a sustainable and vegan alternative to fish oils, algae oil is also free of environmental toxins and thus offers an environmentally friendly option for the daily need for omega-3 fatty acids.
This basic care should be integrated as a daily routine to create a strong foundation for health stability and well-being in neurodegenerative challenges.
DMSO – Versatile application and therapeutic potential in neurodegenerative diseases
Starting with DMSO, one of the key components in the arsenal of health toolbox tools, its versatility and healing power in the context of neurodegenerative diseases is shown. DMSO is known for its anti-inflammatory and immunomodulating properties and has proven to be effective in use in conditions such as multiple sclerosis, Parkinson's disease and other neurodegenerative diseases.
The possible applications of DMSO are manifold and range from large-scale skin wetting to drinking a diluted solution to infusion, which enables individual dosage and treatment depending on the clinical picture and stage. In detail, DMSO is applied externally by spraying a 30% solution, whereby the treatment points such as the belly, back, legs or neck can vary. This application should be done once or twice a day. The solution should work for about 30 minutes after application, without the clothing touching the treated areas. If necessary, dilution can be done with water to minimize skin irritation.
For oral intake, it is recommended to dissolve 2 to 6 teaspoons of pure DMSO in a glass of water. This method supports the internal effect of DMSO, promotes immune regulation and has a regenerative effect on the nerve cells.
In addition to external and oral use, DMSO can also be administered intravenously. For an infusion, DMSO is mixed in a concentration of 7.5 grams with 500 ml of a solution, such as NaCl solution, wrestler solution or ringer lactate solution. Optionally, further agents such as B vitamins, choline bitartrate, acetylcysteine, N-acylglucosamine, galactose, GABA or alpha-lipoic acid can be added to the solution. The infusions are usually carried out 2 to 3 times a week and the flow velocity is regulated between medium and slow, depending on the respective substance, resulting in an infusion period of 45 to 90 minutes.
The healing effect of DMSO is particularly due to the promotion of remyelinization (rebuilding the myelin sheath of nerve fibers), the reduction of edema and the improvement of neurodynamic impulse transmission. As an antioxidant, DMSO protects cells, improves cell nutrition by expanding blood vessels and increases membrane activity and diffusion ability. This leads to an increased oxygen concentration and stabilizes cell functions. In addition, DMSO increases the concentration of acetylcholine in the brain, which is a decisive advantage in neurodegenerative diseases, as it inhibits the breakdown of this important messenger substance. This property is of particular importance, since it contributes to the maintenance of neuronal communication and can potentially slow the progression of neurodegenerative symptoms.
Memory Vital Tincture – Strengthening mental functions and protection against neurodegeneration
After DMSO's versatile uses and effects were explained, we turn to another outstanding healthcare toolbox agent: the memory vital tincture of www.activeMedicus.com , also known as DenkFit. This tincture uses the unique properties of DMSO in combination with proven medicinal herbs to increase mental performance and counter neurodegenerative diseases.
The memory vital tincture is a synergistic blend of ginkgo biloba, Brahmi, Gotu Kola and Greek mountain tea, which specifically aims to improve cognitive function and strengthen memory. These herbs have been known for centuries for their positive effects on the brain and are now combined with DMSO to maximize their effectiveness.
The health benefits of the medicinal plants tincture are manifold:
Neurodegenerative support: Ginkgo and Brahmi are known for their significant positive effects in neurodegenerative conditions such as Alzheimer's and dementia, not only by increasing cerebral perfusions, but also providing comprehensive protection for the nerve cells.
Memory and concentration promotion: The tincture makes a significant contribution to improving memory performance and supports the optimal supply of oxygen and nutrients to the brain cells by promoting blood circulation in the brain.
Mental clarity and perseverance: Brahmi has been shown to support mental clarity and endurance and proves to be beneficial, especially in phases of increased stress levels.
Protection against multiple sclerosis and other neurological diseases: Gotu Kola strengthens neural health and slows down mental degradation.
Antioxidant properties: Greek mountain tea improves attention and protects the brain from oxidative stress.
Improve learning ability: The ingredients of the tincture accelerate the learning process and optimize the recording and processing of information.
The memory vital tincture is therefore not only a means of increasing current cognitive performance, but also serves the long-term protection and promotion of brain health, making it an indispensable component in the prevention and treatment of neurodegenerative diseases.
For detailed information on the application and dosage of the memory-dking tincture, see the following brochure on page 21: https://medicalzumselbermachen.de/wp-co ... ezuege.pdf
Nerve Vital Tincture – Calming and Support for Neurodegenerative Diseases
The nervous vital tincture, also known as RuhePol, is specially designed for calming the nervous system and supporting neurodegenerative diseases. These herbal drops from www.activeMedicus.com combine the calming properties of traditional medicinal herbs with the aim of improving the well-being of people with neurodegenerative complaints.
It contains a balanced blend of green oats, lemon balm, passion flower, lavender and hops, which act synergistically to strengthen the nervous system and ensure a restful sleep. These medicinal herbs are not only known for their calming effect, but also have positive effects on neurological health, making them a valuable resource in treatment and support in neurodegenerative conditions.
The health benefits of the nerve vital tincture include:
Stress reduction and neurodegenerative support: The tincture helps to relieve stress and tension that often come with neurodegenerative diseases and supports neurological function by strengthening the nervous system.
Improved sleep in neurological disorders: Specific ingredients such as hops and lavender promote a deep and undisturbed sleep, which is essential for the regeneration of the brain and the alleviation of neurodegenerative symptoms.
Emotional stability in neurodegenerative challenges: The tincture promotes mental balance and strengthens the emotional resilience of people who are faced with neurodegenerative challenges, which significantly increases their overall quality of life.
By combining these specific medicinal herbs, these medicinal plants tincture provide comprehensive support for people who are facing the challenges of neurodegenerative diseases, and thus become an essential part of their therapy and daily care.
Detailed information on the use and dosage of the nervous vital tincture can be found in the following brochure on page 23: https://medizinzumselbermachen.de/wp-co ... SE-Healing plant forms-Kraeuter droplet urchinszuezuezuezuezuezuezuezuezuezue.pdf
Choline – strengthening the parasympathetic system and promoting healing
Choline, a key molecule in neurotransmission, plays a central role in the parasympathetic part of the autonomic nervous system. As a precursor of acetylcholine, an essential messenger substance, it supports the transmission of nerve impulses and thus promotes the activity of the parasympathetic activity, which is responsible for relaxation and regeneration.
Strengthened in today's often stress-in-fold world, in which the sympathetic nerve cord is often overactive, the strengthening of the parasympathetic nervous system is becoming increasingly important. Choline and its structural relatives, such as choline rat, choline chloride and choline titrat, provide an opportunity to make this compensation. They not only support neurological function and promote healing processes, but also contribute to improving sleep, digestion and reducing anxiety and panic.
Choline can be obtained as a pure substance at www.alchemist.de. For parenteral use of choline, for example in the form of infusions, choline bitartrate is dissolved in pure water and treated as an infusion solution by sterile filtration. For use: Usually about 100 to 200 mg choline equivalents are used for parenteral applications. A formula would be to dissolve 500 mg of choline bit rat in 5 ml of pure water, treat this solution with a sterile syringe filter and transfer it into a 250 ml table salt or ringer infusion solution. In addition, 2 to 7.5 grams of DMSO can be added. The recommended duration of the infusion is 60 to 90 minutes. This direct and effective support of the parasympathetic system can increase the effectiveness in regulating the parasympathetic system, especially when using additives such as DMSO.
These therapeutic approaches provide a comprehensive approach to promote healing and supporting neurodegenerative diseases, sleep disorders and other stress-related complaints. In this context, compounds such as DMAE, Betaine and DEAE are also considered, which also promote or support parasympathetic activity. In addition, GABA and melatonin, which are explained in the further course, as well as essential electrolytes such as magnesium and potassium, play an important role in the regulation of the parasympathetic system by supporting the neurological balance and putting the body in a state of rest and regeneration.
These findings open up a wide range of ways to support the nervous system and improve quality of life by aiming at the body's natural ability to self-regulate and healing.
For further information on Cholin, please refer to a previous newsletter article, which can be found here: https://medizinzumselbermachen.de/rundb ... ympathetic healing-foerdern-cholin-co-understand-und-apply/
Galactose – Essential Brain nutrient with versatile therapeutic use
Galactose, often referred to as “food for the brain”, is an essential part of breast milk and plays a crucial role in the development of the brain during infant life. This simple sugar, which forms together with glucose lactose, is known for its ability to be absorbed without insulin from cells, a property that gives it a special meaning in neurology and in the treatment of neurodegenerative diseases.
With the progression of age, the ability to digest lace decreases, which leads to natural lactose intolerance. This change highlights the need to find alternative sources of galactose to use their beneficial effects without the negative effects of lactating sugar.
Therapeutically, galactose is increasingly being used in the treatment of conditions such as neurodegenerative diseases and diabetes, as it supports cellular nutrition and, in particular, provides energy to nerve cells.
Galactose can be applied effectively by making every day approx. 4 grams, about a heaped teaspoon, dissolved in a glass of water. This solution should ideally be taken 1.5 hours before or after meals to take advantage of the state of sleep in insulin levels and thus improve the intake. For an increased effect, the galactose solution can be enriched with 20 to 30 drops of DMSO (about half a teaspoon). This enriched mixture should then be consumed twice a day, preferably between meals and especially in feelings of hunger. In addition to the galactose-DMSO blend, the intake can be supplemented with an amino acid mixture by adding 1/2 to 2 teaspoons of it. This combination enhances the therapeutic effect and also supports the body in the regeneration and strengthening of the nerve function. This comprehensive method thus provides synergistic support for cellular nutrition and neurological health.
The use of galactose, for example as a drinking solution or infusion, represents a direct way to use this sugar to promote brain health and to support peripheral nerve damage, sleep disorders and other neurological complaints. Detailed instructions for the preparation of galactose infusions can be found in the book “Medicine for DIying”.
In addition, the combination of galactosis with other therapeutic measures, such as regular exercise, sleep optimization, stress reduction and dietary adjustments, can improve insulin receptor function and contribute to regeneration in diabetes. The synergistic effect of galactose with DMSO can also increase cell membrane function and insulin reactivity, thus increasing the therapeutic benefits of these treatments.
Galactose, available in pure form at www.alchemist.de, is therefore not only an essential nutrient source for the brain, but also offers a wide range of therapeutic applications, especially in coping with neurodegenerative diseases and metabolic disorders.
Melatonin – External use for improved sleep and neurological protection
Melatonin is known as the “sleep hormone” and plays an essential role in the round about the human rhythm. It is mainly produced in the pineal gland and regulates the sleep-wake cycle, whereby its production is closely linked to the lighting conditions.
However, the relevance of melatonin goes beyond sleep transport. Research has shown that a lack of this hormone is associated with various health problems, including neurodegenerative diseases such as Alzheimer's and Parkinson's. In addition, melatonin can have neuroprotective properties and is involved in the regulation of mood swings, pain perception and antioxidant protection.
The challenge is the effective administration of melaatonein, since oral forms are often limited in their effectiveness through the digestive process. The external use of melatonin in conjunction with DMSO therefore offers an innovative solution to overcome these limitations. Through transdermal absorption, melatonin can effectively enter the body and develop its comprehensive positive effects without being broken down by the gastrointestinal tract. This method makes it possible to target higher dosages and thus maximizes the therapeutic potential of melatonin.
Application tips for external melatonin:
Start with a low dose to assess the individual response, and customize the dosage as needed.
Apply Melatonin in DMSO dissolved preferably in the evening to support the natural sleep cycle.
Suitable places of appropriate job locations are areas with thin skin such as the inside of the forearms, the abdomen, the inside of the thighs or the knees to ensure optimal absorption.
For detailed instructions on the external use of melatonin, including the recommended dosages and application methods, please refer to the following video: https://youtu.be/EenzPERiAZw.
The use of a ready-to-use mixture of melatonin and DMSO, available for example at www.alchemist.de , offers a promising approach to exploit the full potential of melatonin. This includes, above all, improving sleep quality, protecting the nervous system and promoting overall health.
GABA and amino acids – Central Neurotransmitter for improved brain function
Gamma aminobutyric acid, known as GABA, is a central neurotransmitter in the nervous system of mammals, which has an inhibiting, i.e. inhibiting effect on neuronal activity. This messenger material plays an essential role in regulating synapse activity by preventing abundance of neuronal signals and thus contributing to maintaining neurological balance.
In the healthy body, GABA is synthesized from glutamate, which in turn is derived from glutamic acid – an alpha amino acid that occurs in high-protein foods. It is important to note that GABA itself is neither a proteinogenic nor an alpha amino acid.
The supplementation of GABA, especially in combination with DMSO and other amino acids, has shown positive effects on increasing determination, sense of order, concentration, memory and motivation in children, adolescents and adults. Externally supplied GABA hardly reaches the brain when it is administered alone; therefore, the combination with DMSO makes sense.
Applications of GABA include the treatment of learning difficulties, concentration disorders, developmental delays, attention deficits, neurodegenerative processes, sleep disorders, epilepsy, Down syndrome, and support for healing after birth trauma.
Application and dosage recommendations for GABA:
Drinking solution : A typical dosage of GABA is 0.5 to 2 grams (corresponding to about a good teaspoon tip), mixed with 5 grams of an amino acid mixture. This mixture should be dissolved in about 300 ml of water, juice, smoothie or any other liquid. For improved absorption, 1 teaspoon of DMSO can be added. The recommended intake is 1-2 times a day, preferably in the evening, to use the relaxing and sleep-promoting properties of GABA.
Injection and infusion therapy : GABA may be administered intravenously (i.v.) or subcutaneously (see (see c.). For example, a standard dosage could be 0.5 g GABA in 10 ml 0.9% NaCl solution, to which about 7.5 ml of DMSO are added to in order to increase the uptake and effectiveness of GABA. The recommended flow rate for the infusion is medium, with a duration of approximately 45 minutes.
The optimisation and adjustment of dosages, especially for children, is important. For example, an adapted dosage for children could be half the recommended amount for adults, and the mixture can be dissolved either directly in drinks or smoothies or administered separately (e.g. DMSO over the skin and amino acids in food).
The combination of GABA and the essential amino acids, together with DMSO, provides a promising approach to improving neurological health and promoting general well-being. These products can be obtained at www.alchemist.de, for example.
Vitamin C demonstrated the most substantial difference in average concentration between AD and control groups, followed by significant variances in vitamin D, folate, vitamin E, vitamin A and vitamin B12 levels.
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